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Geltor, Inc. designs recombinant proteins that are produced by its proprietary cellular factories in bulk and at low cost for consumer and technical products. Using its platform technology, Geltor can quickly and inexpensively manufacture proteins for a wide range of industrial customers. Geltor's first product, N-CollageTM, is synthetic collagen sold to brands and ingredient manufacturers in the cosmetics and personal care (C&PC) industry.
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PopBookings, Inc. develops software that streamlines the temporary employment market. With an initial focus on the highly fragmented, $2.2 billion event-staffing segment, the Company's cloud-based and mobile-enabled software automates the hiring, scheduling, attendance, payroll, and performance reporting processes for both employers and 1099 employees.
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Nix is developing a wearable, single-use patch that monitors hydration in real-time, without the need for a power-source or companion device/app. Using a proprietary hydrogel developed at Harvard University, Nix''s biosensor detects changes in an individual''s sweat as he or she dehydrates and rehydrates, including the level of electrolyte losses, indicating when to drink, what to drink, and how much to drink. Dehydration is particularly problematic among athletes, military personnel, laborers, and the elderly, causing a reduction in performance and an increase in hospitalization. Nix''s initial target is the estimated 60 million U.S. amateur and professional athletes, which the Company believes represent a $4.8 billion total addressable market for its product.
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HerdDogg is a data collection and analysis company that improves profitability by enabling ranchers to better monitor and manage the health of their herd. Its patented animal wearable technologies provide animal tracking and aid in the identification of missed heats, illness, and dystocia (difficult births) for the 2.5 billion herd animals worldwide.
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Developer of refrigeration systems designed using thermally-driven heat pump architectures. The company's refrigeration cycle is designed with embedded thermal energy storage, designed to save supermarkets on their low temperature cooling costs and for developing world agricultural applications, to convert 50 degree solar thermal energy into 10 degree refrigeration without electricity, high precision components, or moving parts enabling super markets to avoid peak energy expenses and cool with greater efficiency.
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StreamLink, Inc., based in Cleveland, OH, sells software as a service (SaaS) solutions to nonprofit and public sector entities. StreamLink's Amplifund software enables federal grant recipients to meet the new accounting and reporting requirements of the U.S. Data Act of 2014 regarding their use of grant funds. Its BoardMax software provides a centralized environment for all board of directors-related information and documents.
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GeneMatters is a SaaS and telehealth platform that makes the genetic counseling process 4-5 times more efficient than it is today. Genetic testing is exploding with almost 70,000 genetic tests available today, and approximately 10 new tests added daily. Genetic counselors are in short supply and high demand.
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Bonumose is commercializing low-glycemic index, natural sugars through a proprietary, cost-effective process. Due to public health issues connected to obesity and diabetes, consumer packaged goods firms are reducing traditional, added sugars and ramping their search for alternative sweeteners. The global market for food sweeteners is estimated to reach nearly $111.0 billion by 2020, of which traditional sugars hold an 80% market share. According to estimates, alternative sweeteners have the potential to replace between 2% and 25% of sugar. However, expensive production processes, bitter taste profiles, and poor food functionality, have stymied the growth of alternative sweeteners. Bonumose uses a proprietary enzymatic process to cost effectively convert commodity, agricultural feedstocks (e.g., corn or potato starch) into beneficial, natural sugars with taste and food functionality profiles like those of sucrose.
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Agrilyst helps indoor farm operators use data to make more profitable production decisions. Agrilyst tracks and analyzes all farm data in one place, enabling growers to optimize plant performance and reduce operating expenses.
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Flywheel has developed a cloud-based collaboration platform in which scientists across the world can share reproducible science, work together to advance discovery at an accelerated pace, maximizes R&D spending efficiency, and unlock the true potential of disruptive technologies.
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Cofactor Genomics uses proprietary RNA sequencing technology and machine learning algorithms to diagnose disease. RNA serves as a real-time barometer of a person's health, as opposed to DNA which remains little changed throughout a person's life and whose analysis is estimated to diagnose less than 5% of diseases. Compared to current methods, Cofactor's patent pending RNA isolation technology allows the Company to detect specific RNA molecules from low-quality tissue samples, making 100x more patient specimens available for analysis.
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Agrible sells software that connects the agricultural supply chain from field-to-market, providing critical sustainability, agronomic, and yield data. In an era when consumers demand to know what is grown (e.g., GMO vs non-GMO) and how it is grown (e.g., sustainable, organic, etc.), Agrible is the only solution that provides verifiable visibility from what goes in the ground to what goes in the package, with implications on how agricultural products are grown, traded, transported, processed, and labeled.
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Entac Medical is developing noninvasive devices for predictive and diagnostic medicine based on a novel, patented, platform technology, Previs Audio Spectral Analysis Technology (PASAT). The first application, PrevisEA, is a noninvasive, disposable, self-contained device that is clinically proven to predict postoperative ileus (POI) in surgical patients.
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Neuros Medical, Inc., a Cleveland, Ohio based neuromodulation company, is focused on developing proprietary therapies for unmet needs to patients worldwide. The company's patented platform technology, Altius® Electrical Nerve Block, is focused on elimination of chronic pain in a variety of applications including neuroma/residual limb pain, chronic post-surgical pain, and chronic migraine.
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Indalo Therapeutics (formerly known as Antegrin Therapeutics, Inc.), based in St. Louis, MO is a biopharmaceutical company developing and testing novel compounds that inhibit the development of pulmonary (lung) fibrosis and other fibrotic diseases by inhibiting proteins that are the key drivers of the fibrotic process. Uncontrolled, fibrosis can cause diseased organs to stop functioning.
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ProteoSense is commercializing a proprietary biosensor for food safety testing. Current tests require expensive, specialized equipment and personnel, take anywhere from 12-hours to days, and often require food to be placed on hold until results are available. ProteoSense's high-sensitivity, portable system detects foodborne pathogens in less than 2-hours, reducing test time from days to minutes, an important distinction for perishable foods with a limited shelf life.
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Benson Hill Biosystems, Inc. is a crop design platform that taps the natural genetic diversity of plants to develop healthier, more sustainable and higher yielding food choices. Using its cloud biology computational platform CropOS™, Benson Hill evaluates millions of genetic options, identifying those that optimize traits such as crop yield, nutritional value and resource efficiency with 10X the predictive value of standard methods. The Company then uses plant breeding, transgenics and/or genome editing, including proprietary, patented CRISPR methods, to develop seeds for planting - all in half the time and cost of conventional methods. Benson Hill has made the platform available to partners for use across a broad spectrum of applications from breeding to genome editing to transgenics. Breed, powered by CropOS™, provides decision support that can reduce typical breeding cycles by up to 50%. Edit, powered by CropOS™, which launched in 2017, enhances target selection and optimizes design of genome editing approaches.
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Gila is developing a treatment for obesity using naturally occurring hormones (PYY) known to induce satiety, leading to weight loss. Gila is developing formulations to be applied to the tongue prior to meals, which have successfully induced satiety in animal testing without causing the nausea like symptoms associated with injectable and other formulations.
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Holganix produces and sells 100% organic plant probiotics that significantly reduce the need for fertilizers, herbicides, pesticides, fungicides and water while improving plant vibrancy and yield.
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FairWords automates manual governance processes, using a novel AI-driven platform to automatically review electronic communications going in and out of a company. FairWords' technology saves time and mitigates risk by helping to assure a culture of compliance.
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Euclises Pharmaceuticals is developing and testing novel cyclooxygenase-2 (COX-2, an enzyme responsible for inflammation and pain) inhibitors designed to increase the anti-cancer potency and effectiveness of chemotherapy safely, offering new treatment options for patients suffering from colorectal, non-small cell lung and pancreatic cancers.
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More than just an energy dashboard, the Bractlet platform provides real time analytics, highly predictive forecasts, and continuous, automated energy saving measure identification and ROI analysis for individual buildings and portfolios. Bractlet collects real-time environmental, building- level and equipment-level data, and combines with physics-based simulation technology for a comprehensive approach that allows us to find, forecast, and verify the most effective savings measures.
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Kultevat, Inc., based in St. Louis, MO, combines genetic breeding and chemical process engineering to produce natural rubber from Russian dandelions. There is a strong need to develop a domestic source of natural rubber. Russian dandelions can be grown across wide swaths of the U.S., and produce rubber that matches the characteristics of rubber derived from rubber trees.
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BetterWeekdays, Inc., based in St. Louis, MO, provides a job-matching platform that helps colleges and universities improve job placement outcomes for their graduates and helps employers hire better-qualified candidates based on individual skills and business culture fit. Its software automatically collects and generates more than 1 million live job opportunities and personalizes them to students on their mobile devices, tracking all activity for accreditation and compliance reporting.
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Systematic Revenue, LLC dba Hatchbuck, based in St. Louis, MO, provides all-in-one sales and marketing software designed especially for small to mid-sized businesses. Through its SaaS platform, Hatchbuck combines CRM, email marketing and marketing automation solutions directly to customers by subscription and indirectly through advertising agencies.
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Immunophotonics, Inc., based in St. Louis, MO, is an early stage biotechnology company engaged in the development of a proprietary drug product for use in a minimally invasive therapeutic cancer vaccine (inCVAX) for the treatment of metastatic tumors. The approach is intended to trigger the body's own anti-tumor immune response against cancerous cells. For more information, see http://www.immunophotonics.com.
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Rewards Catering, LLC dba Time to Cater, based in St. Louis, MO, is a web-based full service national catering concierge service used to organize and coordinate catered events from small meetings to multi-location national events. Event hosts enter location, time, attendance and budget information through Time to Cater's free-to-use website and Time to Cater manages the rest.
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Gremln, Inc., based in St. Louis, MO, provides secure social media software for financial service and other regulated industries. Its software combines social media marketing, customer service, monitoring, and the approval processes, filtration and archiving necessary for regulatory compliance (SEC, FINRA, FFIEC), meeting the needs of both a financial services firm’s marketing and compliance departments.
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CrazyForEducation, LLC, based in St. Louis, MO, provides an online database of educational and tutoring programs that teachers and students can access as part of a "Flip classroom;" that is, one in which lecturing occurs primarily outside the classroom while tutoring (homework) is done inside the classroom.
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