Healthcare’s Once-in-a-Generation Disruption
The cost of healthcare in the United States continues to rise and the availability continues to decline. Healthcare spending accounts for 18% of U.S. GDP, and the costs in the U.S. are the highest in the world, increasing 130% in just the last decade. With this complexity comes an opportunity for entrepreneurs, innovators, and investors. iSelect is focused on finding technologies and innovations that reduce costs, increase accessibility, and improve quality of care.
iSelect Portfolio Companies
iSelect focuses on early-stage healthcare companies that are poised to help push the next healthcare revolution forward. We deliberately invest in companies that can make a positive impact on our society, as well as on the bottom line.
Neuros Medical, Inc.
Neuros Medical, a medical device company, develops an electrical nerve block to treat chronic pain for conditions including neuroma/residual limb pain and chronic post-surgical pain. Learn more… 
Cocoon Biotech, Inc.
Fibroin is an insoluble protein that is responsible for silk’s structure and tensile strength. Additional physical properties include tunable viscosity, anti-inflammatory, and wound healing attributes. Cocoon’s fibroin is expected to yield substantial improvements in use-cases such as bio-preservatives, drug or small/molecule delivery, natural lubricants, and hydrogels across numerous industries including human and animal health, agriculture, and consumer products. Learn more…
Nix, Inc.
Nix is developing a wearable, single-use patch that monitors hydration in real-time, without the need for a power-source or companion device/app. Learn more…
MOBILion Systems
MOBILion Systems Inc. has developed ion mobility technology that can separate and identify previously undetectable, clinically significant molecules within minutes, enabling far more accurate disease diagnosis, biomarker discovery, drug discovery, and clinical trial design among other potential applications. Learn more…
Shield Bio
Shield Bio is enabling 3rd generation sequencing to more rapidly and cost effectively diagnose and treat infectious disease while fighting antimicrobial resistance. Learn more…
Molecular Assemblies
Molecular Assemblies is developing an enzymatic DNA synthesis platform technology, enabling new products in industrial synthetic biology, personalized therapeutics, precision diagnostics, data storage, nanotechnology and more. Molecular Assemblies’ novel enzymatic DNA synthesis platform has the potential to fundamentally transform how we write genetic building blocks with applications across food, healthcare, energy, and beyond. Learn more…
Healionics, Inc.
Healionics, Inc. has developed a novel bio-material called STAR, that features strong anti-infective properties and significant reduction in the formation of scar tissue around implanted medical devices coated with the material. Learn more…
Holobiome, Inc.
Holobiome is developing a platform for microbiome-based therapeutics to treat diseases of the central and enteric nervous systems. Learn more…
SciBac, Inc.
SciBac is developing a platform technology called MERGE that enables the Company to efficiently combine desired traits of two microbes into one stable hybrid organism through lab-induced directed evolution. Learn more…
GeneMatters, LLC
GeneMatters is a digital health platform that provides scalable, on-demand genetic counseling to meet the rapidly growing demand for genetic services. Learn more…
Flywheel Exchange, LLC
Flywheel offers a SaaS platform that provides cloud-scale data management and computational analysis. Learn more…
Cofactor Genomics, Inc.
Cofactor Genomics uses proprietary RNA sequencing (“RNA-Seq”) technology and machine learning algorithms to diagnose disease. Learn more…
Entac Medical, Inc.
Entac Medical is developing noninvasive devices for predictive and diagnostic medicine based on a novel, patented, platform technology, Previs Audio Spectral Analysis. Their first product is used to predict post operative ileus after GI surgeries. Learn more…
Indalo Therapeutics
Indalo Therapeutics is developing novel small-molecule therapeutics to differentially treat and prevent the rapidly growing class of fibrotic diseases affecting millions globally. Learn more…
Gila Therapeutics, Inc.
Gila Therapeutics is developing a treatment for obesity using naturally occurring hormones known to induce satiety, leading to weight loss. Learn more…
Euclises Pharmaceuticals, Inc.
Euclises Pharmaceuticals is developing novel enzyme (COX-2) inhibitors designed to increase the effectiveness of chemotherapy safely Learn more…
Immunophotonics, Inc.
Immunophotonics has developed a minimally invasive therapeutic cancer vaccine for the treatment of metastatic solid tumors. Learn more…
Meet Our Selection Committee
Our Healthcare Selection Committee consists of industry and subject matter experts who help guide iSelect’s investment decisions. With firsthand experience and a true pulse on the industry, we consider these individuals key to our success in finding and investing in healthcare innovation.
Resources and News
Therapeutics and Inflammation: What’s Coming Next?
Many of the major medical conditions that we face in our lives share an underlying cause: chronic inflammation.
Investing at the Nexus of Food and Health
Almost three years ago, iSelect strategically refocused its investment thesis on identifying the synergies between food and healthcare. At the time, food and healthcare were two completely independent, siloed verticals. But, the fact is, the more that we understand...
Solving Antibiotic Resistance isn’t a Science Problem, it’s a Business Problem
Antibiotic resistance is one of the primary public health challenges of our time. Most people alive today take antibiotics and the changes they brought to modern life for granted. Before the 20th century, you were as likely to be “cured” by a faith healer or leeches as you were from any actual drug.
System C: The Convergence of Food and Health
We’re here to talk about food system innovation. When we first started this conference, we talked about agtech, and as investors we also focus on healthcare and the convergence of healthcare and agriculture. Innovation is now being discussed as food system innovation. And, so we’ve invited you all and eager to have you participate in the conversation about how we make food improve health and life.
What Researchers are Learning About the Biome Might Just Save Your Life… or Kill You
Over Thanksgiving I overheard some parents talking about their children and dating. Apparently some young adults are now using 23andMe to determine compatibility before a date becomes a serious relationship. The parents mentioned an attempt to sneak some hair and...
How Blood-Based Diagnostics are Changing Cancer Care
iSelect hosts a Deep Dive webinar on a novel innovation topic on the first and third Wednesdays of each month at 9 a.m. central. Our most recent session focused on early cancer diagnosis using blood-based tools. Testing patients for cancer has typically involved a...
What’s the Future of Nutrition? Addiction
The modern world has a serious problem with sugar. The average American consumes more than 129 pounds of the stuff each year, according to the USDA, more than double what we ate two generations ago. And, unlike in previous decades when most sweeteners came from cane...
You Are What You Think: How New Brain Care Advances Are Increasingly Person-Centered
It’s an exciting time in the field of brain science. Researchers are working on new speech analysis tools for the diagnosis of Alzheimer’s. New studies have shown that retina scans can be used to detect early signs of the disease, long before typical symptoms show up....
4 Trends We’re Watching in Healthcare in 2019
Healthcare is massive economic burden in this country. According to the National Health Expenditure Accounts, the federal agency that has tracked healthcare spending in the U.S. since the 1960s, it now totals roughly $3.5 trillion per year, or more than $10,000 per person. As a percentage of GDP, health spending accounts for nearly 18%.
2 Companies That Are Working to Cure Cancer Right Now
In 2018, an estimated 1,735,350 new cases of cancer were diagnosed in the United States and 609,640 people died as a result of the disease, according to the National Cancer Institute. These numbers are staggering. The challenge for clinicians and researchers is...
How Shifting Spending to Healthy Foods Could Prevent Chronic Illness
The burden of chronic health issues is massive: 90% of the nation’s $3.3 trillion in annual health care expenditures are for people with chronic and mental illness, according to the National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP). Even...
Solving the Public Health Crisis by Making Healthy Nutrition as Addictive as Sugar
The modern world has a serious problem with sugar. The average American consumes more than 129 pounds of the stuff each year, according to the USDA, more than double what we ate two generations ago. And, unlike in previous decades when most sweeteners came from cane...
